EPILEPSY相关论文
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目的:采用MR低频振幅(ALFF)分析方法探讨SCN1A基因rs3812718位点多态性对颞叶癫痫患者脑组织自发神经活动的影响。方法:回顾性分析20......
目的:初步探讨三维正电子发射断层显像术(PET)与MRI配准融合技术在儿童药物难治性癫痫术前评估中的应用价值。方法:回顾性分析2019......
Tuberous sclerosis complex (TSC) is a rare multisystem, autosomal dominant neurocutaneous syndrome in which epilepsy is ......
Introduction::Glucose transporter type 1 (Glut1) deficiency syndrome is a treatable neurometabolic disorder characterize......
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目的:分析奥卡西平用于癫痫治疗的有效性及对患者临床症状的影响.方法:治疗方法比较,探讨其临床应用效果,取样88例癫痫患者为本次......
目的:分析在癫痫患者的临床护理中应用心理护理的有效性与满意度。方法:选入样本60例,均为癫痫患者,选入样本时间为2020年1月至2020年1......
目的:对1例癫痫伴全面性发育落后患儿的临床特征及n ZBTB18基因变异进行分析,明确其可能的致病原因,为临床诊断提供依据。n ......
目的:探讨CXCR4特异性拮抗剂AMD3100影响癫痫发作的分子机制。方法:(1)动物实验:36只成年雄性SD大鼠按随机数字表法分为对照组、癫......
目的:探讨“互联网+”医院-家庭-学校照护模式在学龄期癫痫患儿中的应用效果。方法:采用便利抽样法,选取2020年1—12月在徐州市儿童......
目的:研讨神经内科癫痫并发偏头痛的临床特征.方法:选择我院2019年7月~2020年7月神经内科收治的100名癫痫病病患作为研究对象.其中......
目的:研究拉莫三嗪联合丙戊酸治疗癫痫的临床效果.方法:根据治疗方案不同,将88例癫痫患者分为44例/组.对照组予以丙戊酸治疗,观察......
目的 探讨氟桂利嗪抗菌药物联合手术治疗中枢神经系统感染患者继发癫痫的临床效果?方法 根据研究需要,将2017年3月至2019年3月我院......
目前,针对中枢神经系统疾病的常规治疗方法主要是手术治疗和药物治疗。随着光遗传学技术的出现,研究者能够在神经元以及神经环路的水......
Mechanistic target of rapamycin (mTOR) sig-naling governs important physiological and pathological processes key to cell......
分析福建医科大学附属第一医院神经外科于2015年1月至2018年12月收治的49例弥漫性低级别胶质瘤相关癫痫患者的临床、病理特征及术......
目的:评价n 11C-胆碱PET/CT动态脑显像对海马硬化难治性颞叶癫n (HS-RTLE)致n 灶的定位诊断价值,并与n 18F-FD......
目的 探讨丙戊酸钠联合托吡酯治疗癫痫患者的疗效及对炎性反应与氧自由基水平的影响?方法 将2017年5月至2019年5月本院收治的100例......
目的 分析针对癫痫患者采用丙戊酸镁联合拉莫三嗪治疗的临床效果?方法 选取本院收治的80例患有癫痫疾病的患者纳入研究对象,时间为2......
Calorie restriction or dietary restriction: how far they can protect the brain against neurodegenera
Finding the correct nutritional intervention is one of the biggest challenges in treating patients with neurodegenerativ......
Sulfonylurea receptor (SUR) belongs to the adenosine 5′-triphosphate (ATP)-binding cassette (ABC) transporter family; h......
Therapeutic potential of glial cell line-derived neurotrophic factor and cell reprogramming for hipp
Hippocampus serves as a pivotal role in cognitive and emotional processes, as well as in the regulation of the hypothala......
Epilepsy is a brain condition characterized by the recurrence of unprovoked seizures.Recent studies have shown that comp......
无脑回-巨脑回是一组在早期脑发育过程中神经元异常迁移所继发的皮层发育障碍疾病,主要特征为脑回宽大、脑沟浅小、皮层增厚,临床上......
目的 分析左乙拉西坦在癫痫治疗中的应用效果和安全性?方法 研究对象为2017 年2 月至2019 年2 月在我院接受治疗的80 例癫痫患者,采......
Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hipp
Characterizing the three-dimensional (3D) morphological alterations of microvessels under both normal and seizure condit......
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Early hypoactivity of hippocampal rhythms during epileptogenesis after prolonged febrile seizures in
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Epilepsy is one of the most common neurological diseases.Of all cases,70%-80% are considered to be due to genetic factors.......
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Ion Channel Genes and Epilepsy: Functional Alteration,Pathogenic Potential, and Mechanism of Epileps
Ion channels are crucial in the generation and modulation of excitability in the nervous system and have been implicated......
Laminar Distribution of Neurochemically-Identified Interneurons and Cellular Co-expression of Molecu
Inhibitory GABAergic intemeurons are fundamental elements of cortical circuits and play critical roles in shaping networ......
SCN9A Epileptic Encephalopathy Mutations Display a Gain-of-function Phenotype and Distinct Sensitivi
Genetic mutants of voltage-gated sodium channels (VGSCs) are considered to be responsible for the increasing number of e......
Rasmussen\'s encephalitis (RE) is a rare and severe progressive epileptic syndrome with unknown etiology.Infection by ......
Theroleofmagneticresonancespectroscopyinlateralization diagnosisforepilepsy:Ameta-analys
Purpose Thepurposeofthestudyistoevaluatetheroleofmagneticresonancespectroscopyinlateralizationdiagnosisfor epilepsyandex......
Purpose: Neural network disorder has been increasingly recognized and become a key concept of drug-resistant epilepsy (D......
A comparative study between fractional anisotropy and ellipsoidal area ratio of idiopathic generaliz
Objective:To compare and further evaluate FA and EAR measures of diffusion anisotropy in children of idiopathic generali......
Selective strengthening of synaptic inhibition between dentate cannabinoid-sensitive interneurons in
Altered inhibition is asalient featureof hippocampal network reorganization in epilepsy.Dentate granule cells show reduc......
The pro-inflammatory cytokine interleukin-1β is a key regulatory factor for the postictal suppressio
The postictal suppression(PS)is a common and important period following an epileptic seizure but has not been well studi......
Study on the effect of Neuropeptide(Nesfatin-1)on epileptic discharges in rat insular cortex neurons
Nesfatin-1 is the discovered peptide hormones involved in the control of appetite in 2006....
Quantitative features of SCN1A associated epilepsies:relationships among genotype,functional alterat
Mutations in SCN1A gene have been identified in epilepsies with widely variable severity,ranging from the extremely seve......
Objective Penicillin epilepsy model,whose discharge resembles that of human absence epilepsy,is one of the most useful a......
Objective N-methyl-D-aspartate(NMDA)receptors play important role in neurological diseases,including epilepsy....
Seizure is a common neurological disorder which affects 1%of population worldwide....